Wellcome

Reimagining Global Health Architecture for a Changing World

Global health is at an inflection point. Declining development assistance, shifting political priorities, and a more complex geopolitical landscape are placing long-standing systems of international cooperation under strain. At the same time, this disruption presents an opportunity to rethink how global health architecture can better serve countries and communities in a rapidly changing world.

To help shape this moment, Wellcome commissioned five Regional Dialogues to explore priorities and pathways for reform. The Europe and North America Regional Dialogue—co-led by Panorama Strategy and SEEK Development—brought together leaders from government, civil society, philanthropy, multilateral institutions, and academia. Through stakeholder consultations, a joint survey, and an in-person convening on the sidelines of the World Health Summit, participants examined gaps in the current system, identified urgent areas for reform, and explored how actors in Europe and North America can advance a more coherent and equitable approach to global health.

The resulting report synthesizes these insights and outlines practical pathways for change. As global health stakeholders reconsider how to collaborate in a shifting environment, this dialogue provides a timely foundation—and a call to build a more sustainable, inclusive architecture that delivers healthier futures for all.

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Photo courtesy of Wellcome (2025)